A weekly e-journal by Art Epstein, OD, FAAO

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Volume 18, Number 23

Monday, June 5, 2017

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Inside this issue: (click heading to view article)
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######### Off the Cuff: Ch-Ch-Changes
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######### Corneo-scleral Limbal Changes Following Short-term Soft Contact Lens Wear
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######### Assessment of Optic Nerve Head Pallor in Primary Open-angle Glaucoma Patients and Healthy Subjects
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######### Risk of Progression in Macula-on Rhegmatogenous Retinal Detachment
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######### News & Notes
 

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Off the Cuff: Ch-Ch-Changes

As David Bowie sang:
“I watch the ripples change their size
But never leave the stream
Of warm impermanence
And so the days float through my eyes
But still the days seem the same”

Bowie was a keen, if not prescient, observer of the world. We are only just beginning to see what he saw. In our small universe, at this moment, things seem unchanged; yet, the world is impermanent, and changes are coming that will wash over us in unrelenting waves.

Yesterday, you were worried about Opternative. As I write this, a few surviving independent opticians up and down the East and West Coasts—notably areas with the highest concentration of eye care providers—are finally seeing their dreams come true. No more need for an OD or the rare moonlighting ophthalmology resident to do refractions, and no matter that the opticians were never able to win that right for themselves, they have replaced trained and licensed eye care professional with the SVOne—a portable Hartmann-Shack wavefront aberrometer that attaches to a smartphone.

While the opticians never had the political clout, financial resources or public health justification to gain refraction privileges, Smart Vision Labs, the creator and distributor of the SVOne, has achieved most of the first two and is hard at work trying to convince the public and legislators of the third. For what it’s worth, the device works as well as a modern autorefractor, which was astonishingly validated in an article authored by two noted SUNY researchers and published in our very own Academy journal. I wonder if SUNY encloses the article in their applicant information package?

While you would think that this clearly would be practicing optometry without a license and that optometry boards in NY and CA would be up in arms, so far these opticians have been able to skirt existing laws by using ophthalmologists with time on their hands to sign off on prescriptions for patients they’ve never actually seen. While this might be gratifying to the few remaining antediluvian MDs who hate optometry, technology is, indeed, a harsh mistress, and the technology shoe will soon be on the other foot. Automated and autonomous cataract surgery isn’t that far down the stream, and what goes around, indeed, comes around. 

Our own inter-professional war must come to an end. Somehow optometry and ophthalmology must find a path to cohesion. Working together is the only way to ensure our patients’ safety and channel technology for good rather than greed and profit.

 

 


Arthur B. Epstein, OD, FAAO
Chief Medical Editor
artepstein@optometricphysician.com

 

Want to share your perspective? Write to Dr. Epstein at artepstein@optometricphysician.com.

The views expressed in this editorial are solely those of the author and do not necessarily represent the opinions of the editorial board, Jobson Medical Information LLC (JMI), or any other entities or individuals.

 





Corneo-scleral Limbal Changes Following Short-term Soft Contact Lens Wear
 
 
Twenty-two neophyte subjects wore soft contact lenses for a period of five hours to assess whether short-term soft contact lens wear alters the anterior eye surface. Topography-based corneo-scleral limbal radius estimates were derived from height measurements acquired with a corneo-scleral profilometer. Additionally, central corneal thickness (CCT), anterior chamber depth (ACD), corneal curvature radius (R) and white-to-white (WTW) diameter were acquired with an OCT-assisted biometer. Measurements were obtained without lens wear (baseline) immediately after lens removal following five hours of wear, and three hours after lens removal.

Short-term soft contact lens wear significantly modifies corneo-scleral limbal radius (mean ±SD: 130 ±74μm), and the changes are repeatable. In contrast, the WTW diameter and R were not modified. ACD and CCT were significantly affected, but no significant correlations were found between the increment of the limbal radius and the decrease in ACD and CCT. Limbal radius increment was reversed three hours after lens removal for 68% of the subjects, but the time course of this reversal was not uniform.

It is possible to accurately quantify limbal radius changes as a consequence of soft contact lens wear. The increment in the limbal diameter could reach over 0.5mm but that alteration does not correspond to changes in WTW diameter, and it was not observable to the examiner using a slit lamp. Assessing topographical limbus after contact lens wear could be a tool to optimize the selection of the contact lens, from the perspective of anterior eye surface changes.


SOURCE: Consejo A, Bartuzel MM, Iskander DR. Corneo-scleral limbal changes following short-term soft contact lens wear. Cont Lens Anterior Eye. 2017; May 24. [Epub ahead of print].







Assessment of Optic Nerve Head Pallor in Primary Open-angle Glaucoma Patients and Healthy Subjects
 
 
This study investigated optic nerve head (ONH) pallor quantitatively in patients with primary open-angle glaucoma (POAG) and in healthy subjects, and examined the relationship to mean deviation in perimetry (MD), cup-disk ratio (CDR) and diameters of retinal vessels. A total of 89 POAG patients (67.6 years ± 11.1 years) and 48 healthy subjects (63.3 years ± 14 years) were included. A dual-bandpass transmission filter was introduced in the illumination path of the fundus camera of the Dynamic Vessel Analyzer (Imedos Systems UG) and two monochromatic images at different wavelenghts (548nm ± 10nm and 610nm ± 10nm) were recorded simultaneously. ONH pallor was defined as the quotient of light reflection in both spectral channels. Pallor values were averaged over four fields that were positioned on the ONH. The mean of these measurements was calculated. In 47 of 89 POAG patients, diameters of retinal vessels were determined peripapillary.

In POAG, the ONH showed a significantly higher pallor value compared with healthy subjects (82.34 ± 19.28 vs. 62.67 ± 10.41). ONH pallor was correlated with indicators used to estimate disease severity: MD and CDR. The pallor value was associated to diameters of retinal arterioles and venules.

Pallor determined by this method was higher in POAG patients than in healthy subjects and increased in patients with advanced disease. ONH pallor might result from a reduced blood perfusion of the ONH or tissue atrophy accompanied by vessel obliteration in POAG. By measuring ONH pallor, additional diagnostic information about the vitality of the neuroretinal rim might be gained in glaucoma patients.


SOURCE: Ramm L, Schwab B, Stodtmeister R, et al. Assessment of optic nerve head pallor in primary open-angle glaucoma patients and healthy subjects. Curr Eye Res. 2017; May 30. [Epub ahead of print].

 

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Risk of Progression in Macula-on Rhegmatogenous Retinal Detachment
 
 
Patients referred for surgery due to primary rhegmatogenous retinal detachment with the macula on between 2009 and 2013 were included to identify factors that may lead to a rapid progression in macula-on rhegmatogenous retinal detachment (RRD); in particular, those that may lead to macular involvement. Relevant factors analyzed included age, time delay until surgery, lens status, myopia, the detachment's location and configuration, as well as number, size and type of retinal breaks. Eyes underwent optical coherence tomography to detect macular detachment. A multivariate analysis was performed to investigate the effect of several factors in the progression of retinal detachment.

A total of 116 eyes of 116 patients were included. Mean time delay between admission and surgery was 1.8 days ± 1.4 days. Progression was observed in 19.8% of the eyes. Of those, 47.8% presented macular detachment. Ten of the 11 (90.9%) eyes presenting progression involving the macula also exhibited a bullous configuration, which was the only parameter that correlated significantly with detachment progression in patients with (p=0.0036) and without (p=0.0014) macular involvement.

Researchers wrote that for the first time in a prospective trial, a bullous configuration was found to be a highly significant predictor for progression in macula-on detachments. The data supported prompt surgery in patients diagnosed with bullous macula-on RRD.

SOURCE: Callizo J, Pfeiffer S, Lahme E, et al. Risk of progression in macula-on rhegmatogenous retinal detachment. Graefes Arch Clin Exp Ophthalmol. 2017; May 27. [Epub ahead of print].








News & Notes
 
Bausch + Lomb Introduces renu Multipurpose Solution
Bausch + Lomb renu advanced formula multipurpose solution for soft and silicone hydrogel contact lenses combines three disinfectants and two surfactants for effective cleaning and disinfection, and all-day comfort. The new offering will be the only renu solution on the market, replacing renu sensitive and renu fresh, beginning in June 2017 at major retailers. Read more.

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Alcon Unveils New Packaging for Dailies AquaComfort
Alcon launched new packaging for Dailies AquaComfort Plus spherical contact lenses in 90-, 30- and five-packs to assist individuals with proper lens wear and care. The design features patient-friendly educational elements, including: detailed insertion and removal illustrations; a toll-free patient helpline and email address; and the Dailies website address for more at-home and online support. Additionally, the U.S. flag will appear on the new packaging to identify the boxes. U.S.-specific lot numbers will also enhance supply chain tracking capabilities. By the end of 2017, Alcon also plans to launch the packaging for Air Optix plus HydraGlyde contact lenses.




Essilor Celebrates Anniversary of Mr. Orange With Special Offer
Essilor Instruments is offering a six-year warranty for every order placed between June 1 and July 31 to celebrate the sixth anniversary of the Mr. Orange edger. In 2011, Mr. Orange won the SILMO d’Or award and was endorsed in 2014 with the Pont d’Or award from Inform’ Optique magazine, where roughly 11,000 opticians rank their favorite suppliers. Eye care professionals are encouraged to contact their Essilor Instruments sales representatives for details on the warranty coverage. Read more.


Avedro Corneal Collagen Cross-linking Phase III Keratoconus Study Results Published
Avedro announced the publication of one-year safety and efficacy data from the randomized, controlled Phase III clinical trials that supported the FDA approval of Avedro’s Photrexa Viscous (riboflavin 5’-phosphate in 20% dextran ophthalmic solution), Photrexa (riboflavin 5’-phosphate dextran ophthalmic solution) and KXL System for the treatment of progressive keratoconus. Results from the clinical trials, in which 205 individuals with progressive keratoconus were treated at multiple U.S. sites, were published in Ophthalmology.

TearClear Completes $4.5M Series A Financing, Introduces Leadership Team
TearClear announced the completion of its Series A financing, with proceeds totaling $4.5 million. The round was co-led by Visionary Venture Fund and Bluestem Capital. The company’s chemical filter removes benzalkonium chloride at the point of instillation, enabling multidose product preservation until the moment of application. In addition, the company assembled a team of ophthalmology veterans to drive the development of its filter technology. Read more.

 
New Technologies and Treatments in Eye Care 2017 - Orlando, Florido
 
 
 
   

Optometric Physician™ Editorial Board
 

Chief Medical Editor
Arthur B. Epstein, OD, FAAO

Journal Reviews
Shannon Steinhäuser, OD, FAAO


Contributing Editors
• Katherine M. Mastrota, MS, OD, FAAO
• Barry A. Weissman, OD, PhD, FAAO (Dip CL)

Editorial Board
• William Jones, OD, FAAO
• Alan G. Kabat, OD, FAAO
• Bruce Onofrey, RPh, OD, FAAO
• John Schachet, OD, FIOS
• Joseph Shovlin, OD, FAAO


 

 

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