Timely reports on clinical research, legislative updates and product launches, from the editors of Review of Optometry and RCCL. Stories post each weekday morning.
Also, safety profile doesn’t necessarily correlate with popularity, ARVO study shows. Regulatory oversight could improve public safety, researchers suggest.
While only 1.2% of keratoconic eyes required either repeat treatment or corneal graft surgery, the procedure’s failure was more likely to occur with these factors in the patient history.
From 2011 to 2021, there was a decline in traditional trabeculectomies while minimally invasive procedures such as iStent, goniotomy and transluminal dilation showed substantial increases.
A 5mm design induced a greater corneal power shift than a 6mm version, with corresponding better effects on axial length growth in a recent ARVO paper.
Inserts imbued with copper were shown to enhance lysyl oxidase activity. Early results look promising and will continue to receive development in hopes of eventual commercialization.
Re-epithelialization was faster and more successful with the treatment vs. conventional methods. Studies found positive effects in cases used for neurotrophic keratitis and ulcers.
One paper helped isolate ocular hypertensives at a low risk of disease conversion. The other screened high- and low-risk patients and found a correlation between PRS and new diagnoses of POAG.
An ARVO paper focusing on ocular surface conditions in kids also shows high-potency corticosteroids were used most often in blepharokeratoconjunctivitis.
Research using ultra-widefield imaging showed that assessment of the entire retina is important to more accurately stratify disease progression risk in vulnerable patients.
The BLINK2 study followed children and teenagers for an additional year after they wore such lenses for two years. Axial length and refraction were maintained.
Mesopic dysfunction was found following previous predominant rod-mediated function loss, whereas the overall highest functional loss was detected with development of cRORA lesions.
Following cataract surgery, the pathology developed in 23% of eyes with filtering lens implants and 19% without. Mean annual increases, however, were 0.78mm2 and 1.26mm2, respectively.
The most significant inner retinal alterations were observed in those with late-stage disease and/or GA, while little difference was noted between early and intermediate macular degeneration.
Researchers speculate that the ensuing stagnation may cause an accumulation of neurodegenerative factors; another theory involves compartmentalization of the optic nerve sheath.
As this impacts corrected-distance VA and hence treatment decisions, clinicians need to consider ways to bring more consistency to their workups, study argues.
The neurodegenerative disease can be difficult to track in terms of remyelination, but certain agents can be monitored through ocular imaging to gauge efficacy.
Bausch + Lomb previewed a forthcoming product and pointed to company-funded research showing treatment effects possible after two, four and eight weeks of daily use.
This revision—accounting for reticular pseudodrusen and GA—shows that progression rates are substantially higher when using a more comprehensive approach.