Timely reports on clinical research, legislative updates and product launches, from the editors of Review of Optometry and RCCL. Stories post each weekday morning.
The neurodegenerative disease can be difficult to track in terms of remyelination, but certain agents can be monitored through ocular imaging to gauge efficacy.
Bausch + Lomb previewed a forthcoming product and pointed to company-funded research showing treatment effects possible after two, four and eight weeks of daily use.
This revision—accounting for reticular pseudodrusen and GA—shows that progression rates are substantially higher when using a more comprehensive approach.
A Danish study of 30,000 patients found increasing age, female sex and low comorbidity score were correlated with better diligence with eye drop treatment for up to 10 years.
The noninfectious form was helped by periocular and intraocular corticosteroids. Newer delivery methods have less evidence supporting their use due to the recency of their introduction.
Fovea-to-disc distance, location of the superior and inferior peaks of the cpRNFL thickness curve, and estimated axial length all correlated with RNFL thickness more so than age and disc area in a new study.
The inflammatory retinal condition presented a central-to-peripheral gradient of improvement that may suggest specific peripapillary vulnerabilities, researchers suggest.
Candida, Aspergillus and Fusarium were the most common organisms. Patients with filamentous keratitis had different risk factors, better outcomes and decreased need for surgical intervention compared to yeast keratitis.
Most rely on artificial tears more so than eyelid-based interventions, 22% spend an hour or more daily on care and less than half reported that their primary source of information is their eyecare provider.
Patients taking GLP-1 agonists had a higher rate of progression to proliferative retinopathy and new-onset macular edema than those on SGLT-2 inhibitors.
These lenses were shown to be safe and effective, but were noted to decrease low-contrast visual acuity at distance. Ortho-K also was deemed a bit more effective but also more prone to adverse effects.
Patients with low glomerular filtration rates and high glycated hemoglobin levels fared worse in this study, highlighting the need for continuous monitoring of systemic health.
Using AI to characterize the ‘fractal dimension’—or branching patterns—of the vasculature yielded associations with disease prevalence in adults of all ages.
Study also finds intraretinal fluid results in a fast-progressing disease, and these patients tend to be older at the time of diagnosis and remain on treatment for a shorter time.
While only being tested on animals right now, clinical application might emerge in time as more studies solidify its positive effects. The mechanism may involve changes to scleral and choroidal development during ocular growth.
Study finds approximately 96% of counties lack specialists among both optometrists and ophthalmologists, with lower socioeconomic areas the most severely affected.
Understanding these features may help disease diagnosis in Asian populations. Patients with the former subtype were significantly younger, predominantly male and had a slower progression rate.
Though patterns of damage varied widely in a new study, no eye was spared disease progression in this vital area, underscoring the need for close monitoring with OCT.