AMD Staging: More Than Wet Vs. Dry

Various imaging biomarkers can help you get a truer sense of disease status and predict a patient’s risk of progression. Here’s what to look out for.

Melatonin Shown to Decrease Risk of AMD Development and Progression

Researchers acknowledged that lifestyle changes may have also contributed, but nevertheless speculated that the drug may reduce oxidative stress and subsequent VEGF overexpression.

Personalized Wet AMD Management with At-Home OCT Possible

While from a small study of 27 eyes, recent findings showed an almost 50% reduction in treatment burden while maintaining stable visual acuity.

Low-dose Aspirin Not Effective in Preventing AMD

The regimen also wasn’t helpful in slowing or preventing progression of the disease.

High-dose Aflibercept Pushes Dosing Interval to Five Months

Nearly half of subjects went 20 weeks or longer between injections with the 8mg formulation. The regimen also maintained BCVA gains out to 96 weeks.

PED Lesions, Hyperreflective Foci Associated With Visual Decline in Dry AMD

Mesopic dysfunction was found following previous predominant rod-mediated function loss, whereas the overall highest functional loss was detected with development of cRORA lesions.

Meta-analysis Associates Three Air Pollutants with AMD Risk

The relationship was not causal, suggesting that more research is needed to elucidate the underlying mechanisms.

Study: Blue-Light IOLs Can Reduce Progression of Macular Atrophy, But Not Incidence

Following cataract surgery, the pathology developed in 23% of eyes with filtering lens implants and 19% without. Mean annual increases, however, were 0.78mm2 and 1.26mm2, respectively.

Ganglion Cell Complex Thickness Reduced in AMD

The most significant inner retinal alterations were observed in those with late-stage disease and/or GA, while little difference was noted between early and intermediate macular degeneration.

Three Home-monitoring Vision Tests for nAMD Fall Short in Diagnostic Accuracy

The options called KeepSight, MyVisionTrack and MultiBit are not yet ready for implementation in clinical practice, researchers say.

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June 19, 2024

Showcasing Inflammation and IOP Control
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Presenters: Nora Lee Cothran, OD, and Walter Whitley, OD, MBA
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Current Thinking in Dry Eye Disease: Contemporary Perspectives on a Complex Condition
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