In a study that investigated the relationship between OCT parameters and long-term visual outcomes following optic chiasm decompression surgery, researchers found that preoperative RNFL thickness was associated with long-term visual recovery. The prospective cohort study included 239 patients (mean age 52 ±16 years) who had undergone pituitary or parasellar tumor resection between January 2009 and December 2018. 

Pre- and post-op assessments included best-corrected visual acuity, visual fields, OCT RNFL thickness, macular thickness and volume. Long-term improvements (assessed at 24 months post-op) in visual field recovery and maintenance were defined as a mean deviation greater than -3; for visual acuity, this was defined as Snellen 20/20. Multiple analyses showed that increased superior and inferior RNFL thickness (per 10μm) were associated with higher odds of long-term visual field recovery and maintenance.

The researchers developed a multivariate risk prediction model that they say may assist with preoperative patient counseling and prognoses.

Wang M, King J, Symons R, et al. Prognostic utility of optical coherence tomography for long-term visual recovery following pituitary tumor surgery. Am J Ophthalmol. June 10, 2020. [Epub ahead of print].