In an effort to update our understanding of the geographic distribution of AMD incidence based on recent literature, researchers recently performed a review and meta-analysis of studies that employed a standardized photographic assessment and classification system.

Their search yielded 24 population-based studies, which included a total of 70,123 individuals aged 55 or older. From this, the researchers found the pooled global annual incidences of early and late AMD were 1.59% and 0.19%, respectively. Those of European descent had the highest annual incidence of both early and late AMD compared with other ethnic groups.

The researchers also noted that average age at baseline, ethnicity, region and sex were predictors for incidence of late AMD, while only average age at baseline and ethnicity were associated with incidence of early AMD.

The researchers concluded that their study, which pulled publications up until September 2019, offers an up-to-date overview of global incidences of AMD. They suggest that their findings “may provide scientific guidance for the design and implementation of public health strategies such as screening programs for AMD in both specific geographic locations and ethnic groups, as well as worldwide.”

Zhou M, Duan P-C, Liang J-H, et al. Geographic distributions of age-related macular degeneration incidence: A systemic review and meta-analysis. Br J Ophthalmology. September 9, 2020. [Epub ahead of print].