Researchers in Tianjin, China assessed the corneal biomechanical difference between the low myopic eyes and high myopic eyes, and discovered that high myopia may be associated with low corneal hysteresis (CH), low corneal resistance factor (CRF) and high intraocular pressure (IOP). They believe that determining the influence of biomechanical parameters on myopia is important for the analysis of the underlying mechanisms of high myopia.

The systematic review assessed 835 low myopic eyes and 1027 high myopic eyes by combining the results of 11 studies. CH and CRF were significant higher in the low myopic eyes, with the mean differences of 0.73mm Hg and 0.20mm Hg, respectively. The study also analyzed both corneal-compensated and Goldmann-correlated IOP. The two parameters were higher in high myopic eyes, with mean differences of -2.53mm Hg and -1.42mm Hg, respectively. Researchers found no significant difference in central corneal thickness between the two groups.

The study concluded that future research should examine the underlying corneal structure difference that causes the low CH and CRF value it found in eyes with high myopia. 

Wu W, Dou R, Wang Y. Comparisons of the corneal biomechanics between low and high myopic eyes –a meta-analysis. Am J Ophthalmol. July 30, 2019. [Epub ahead of print].