When deciding which technology is best to detect glaucoma defects in myopia patients, a new study in the American Journal of Ophthalmology suggests swept-source OCT (SS-OCT) may be more accurate and have greater diagnostic accuracy in primary open-angle glaucoma (POAG) than spectral-domain OCT (SD-OCT). The team of researchers attributes their finding to SS-OCT's wider scan and measurement area.

The prospective, case-control study included 150 myopic POAG eyes and 100 healthy myopia-only eyes that underwent SD-OCT and SS-OCT in random order on the same day. The investigators rated the locations of glaucomatous defects on both SD-OCT and SS-OCT maps, and compared the maps’ accuracies.

The investigators found the SS-OCT wide-field RNFL thickness maps showed the best accuracy for glaucomatous defect in the inferotemporal (96.4%) and superotemporal (92.4%) regions. The instrument’s RNFL/GCL++/GCL+ wide-field thickness map showed better accuracy for glaucomatous defect in both the superotemporal and inferotemporal regions compared with the SD-OCT thickness map. Additionally, the average GCL++ (87.6%) and GCL+ (87.5%) thicknesses were significantly more accurate for myopic POAG compared with GCIPL thickness from SD-OCT (83.8%).

“It is certainly worth taking advantage of this new technology for accurate diagnosis of POAG and prevention of unnecessary glaucoma treatment in healthy myopic eyes,” the researchers wrote in their paper.


JS, Park KH. Diagnostic accuracy of wide-field map from swept-source optical coherence tomography for primary open-angle glaucoma in myopic eyes. Am J Ophthalmol. June 20, 2020. [Epub ahead of print].